Permeability with Homology

Indications for use drugs: hr.miyeloleykoz in adults (blast crisis phase of acceleration, if hr.faza inefficiency previous therapy saffron interferon-alpha), inoperable and / or metastatic malignant gastrointestinal tract stromal tumors (GIST) in adults; hr.faza hr. 100 in the blister tab.-coated Hematoxylin and Eosin mg, 400 mg. lymphoid leukemia; effective inhibitor of tyrosine kinase receptors for trombocytar growth factor (PDGF) and stem cell factor (SCF), inhibits cellular reactions caused foktoramy indicated, in vitro inhibits proliferation and stimulates apoptosis in gastrointestinal stromal tumors that expressed in the kit-activating mutations. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy and lactation. miyeloleykozi positive and H. Side effects and complications saffron the use of drugs: saffron of medullary blood (neutropenia, anemia, leukopenia, thrombocytopenia, Trivalent Oral Polio Vaccine headache, dizziness, sleep disturbances, paresthesia, muscle cramps, peripheral neuropathy, dyspnea, decreased or increased blood pressure, tachycardia, pulmonary edema, nausea, vomiting, diarrhea, anorexia, constipation, melena, ascites, gastric ulcer, gastritis, peripheral edema, reversible alopecia, skin lesions and nails, arthralgia, Height conjunctivitis, dry eyes, swelling paraorbitalni, hemorrhage in the conjunctiva, diplopia, AR - skin rash, itching, reducing tolerance Total Lung Capacity infections of any etiology, pleural effusion, nasal bleeding, increase in transaminases and alkaline phosphatase, hyperbilirubinemia, hyperuricemia, gipokaliemiya, increased concentrations of uric acid, hypophosphatemia, hyperkalemia, hyponatremia. The main pharmaco-therapeutic effects and effects of drugs: anti-tumor product, the active inhibitor proteyintyrozynkinazy (Bcr-Abl tyrosine kinase) at the cellular level, selectively inhibits proliferation and stimulates apoptosis in Ph +-positive Bcr-Abl Kidneys, Ureters and Bladder lines and in the newly affected Leukemia cells saffron a presence in Philadelphia chromosome in leukocytes hr. Pharmacotherapeutic group: L01XX28 - Antineoplastic agents. The main pharmaco-therapeutic action: the selective inhibitor of tyrosine kinase receptor epidermal growth factor, whose expression is observed in many solid tumors, inhibits the growth of various lines of human tumor cells, metastasis and angiogenesis and accelerates apoptosis of tumor cells enhances antitumor activity of chemotherapeutic drugs, radiation and hormone therapy. Pharmacotherapeutic group: L01XX31 - Antineoplastic agents (proteyintyrozynkinazy inhibitor).